EGAPP Working Group Recommendations

 

Disease/Condition
Genetic Test/Purpose
Test Use
EGAPP™ Recommendation
Breast Cancer: Can tumor gene expression profiling improve outcomes in patients with breast cancer? Prognostic: association of genetic markers with disease severity, progression Insufficient evidence to recommend for or against use
Read the EGAPP recommendation Adobe PDF file [PDF 455 KB]External Web Site Icon (January 2009)
Colorectal Cancer: Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives Diagnostic: association of a genetic marker with a disease/condition in a person with symptoms Sufficient evidence to recommend use for the benefit of relatives
Read the EGAPP recommendation Adobe PDF file [PDF 220 KB]External Web Site Icon (January 2009)

 

 Can UGT1A1 genotyping reduce morbidity and mortality in patients with metastatic colorectal cancer? Pharmacogenomic: predicting response to drug treatment Insufficient evidence to recommend for or against use
Read the EGAPP recommendation Adobe PDF file [PDF 201 KB]External Web Site Icon (January 2009)
Depression: Testing for cytochrome P450 polymorphisms in adults with nonpsychotic depression treated with selective serotonin reuptake inhibitors Pharmacogenomic: predicting response to drug treatment Insufficient evidence to recommend for or against use, but use discouraged pending further research
Read the EGAPP recommendation Adobe PDF file [PDF 225 KB]External Web Site Icon (December 2007)

 

Page last updated: May 5, 2010
Page last reviewed: December 23, 2008
Content Source: EGAPP Team