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Summary: An evidence review involves many steps and is meant to synthesize available evidence on a particular disorder, test, and clinical scenario.
CDC commissions systematic evidence reviews using two strategies:
Evidence reports, the products of these reviews, are detailed, systematic, objective assessments of the available scientific and
clinical evidence on a specific topic. Evidence reports are the basis for deliberations by the EGAPP Working Group as they develop
their Recommendation Statements.
Who is involved: CDC commissions the review, the EWG develops the key questions to be addressed, and the selected review team (e.g., EPC or other contracted group) conducts the review and produces a report. The review team establishes a Technical Expert Panel (TEP) to provide guidance, usually including topic experts and two to three EWG members.
Transparency: All EGAPP Working Group members, review team members, and consultants disclose potential conflicts of interest
for each topic considered. Evidence reports undergo external expert review. Reports or manuscripts published with CDC staff as authors may undergo CDC clearance.
Comprehensive EPC Reviews
Rapid and/or Targeted Reviews
Conducted by Agency for Healthcare Research and Quality Evidence-based Practice Centers
Conducted by reviewers who may include:
Page last updated: July 19, 2010
Page last reviewed: December 23, 2008
Content Source: EGAPP Team